A staged approach to implementing hereditary cancer risk assessment guidelines for large-scale testing

Pilot Study 2 co-leads Knerr and Tuzzio are partnering with Kaiser Permanente Washington to identify promising strategies for implementing hereditary breast cancer risk assessment guidelines. Current clinical guidelines recommend routine ascertainment of individuals who are at increased risk of hereditary breast and ovarian cancer in order to facilitate timely access to counseling, testing, and risk-management. In spite of this expectation, approximately 80% of eligible women have never discussed genetic testing with a health professional. 

This study leverages an existing implementation effort in Kaiser Permanente Washington to increase access to cancer genetic services. Using OPTICC Stage I and Stage II methods, Pilot Study 2 will match implementation strategies to high priority determinants for routine hereditary cancer risk assessment and delivery of genetic testing, and evaluate a staged, stakeholder-driven approach to program implementation planning.

This study will generate usable knowledge for optimizing program implementation while testing the acceptability, feasibility, and usefulness of Stage II methods with stakeholders.

Implementation Science Knowledge Gained

Prioritized barriers and promising strategies to implement hereditary breast cancer risk assessment guidelines for large-scale testing.

Research Team

Sarah Knerr, PhD

Study Co-Lead

Leah Tuzzio, MPH

Leah Tuzzio, MPH

Study Co-Lead